GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS
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چکیده
منابع مشابه
GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS
Genome-wide association studies (GWAS) evaluate associations between genetic variants and a trait or disease of interest free of prior biological hypotheses. GWAS require stringent correction for multiple testing, with genome-wide significance typically defined as association p-value <5*10-8. This study presents a new tool that uses external information about genes to prioritize SNP association...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0162466